---
title: "Arizona APOE Cohort Study"
id: "4276"
type: "cohort"
slug: "banner-health-apoe-longitudinal"
published_at: "2022-12-13T19:12:51+00:00"
modified_at: "2024-11-27T16:03:58+00:00"
url: "https://dss.niagads.org/cohorts/banner-health-apoe-longitudinal/"
markdown_url: "https://dss.niagads.org/cohorts/banner-health-apoe-longitudinal.md"
excerpt: "Cognitively unimpaired 50-90-year-old persons with each common form of APOE genotype providing blood and cerebrospinal fluid samples obtained utilizing the NCRAD protocol with storage and management through NCRAD, amyloid and tau PET and MRI brain imaging data compliant with the..."
taxonomy_cohort_categories:
  - "ADSP"
taxonomy_cohort_countries:
  - "United States of America"
---

## Description

Cognitively unimpaired 50-90-year-old persons with each common form of APOE genotype providing blood and cerebrospinal fluid samples obtained utilizing the NCRAD protocol with storage and management through NCRAD, amyloid and tau PET and MRI brain imaging data compliant with the SCAN Initiative, and cognitive and behavioral assessment data including the NACC UDS.

Once a year, participants will provide blood samples for clinical lab analysis and genetic testing. Every two years, participants will provide cerebrospinal fluid samples, undergo PET and MRI brain scans, and complete a series of tests to assess cognitive function, risk factors, and other measures.

## Related Datasets

- [NG00067 – ADSP Umbrella](https://dss.niagads.org/datasets/ng00067/) This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common… [Learn more](https://dss.niagads.org/datasets/ng00067/)

## Related Studies

- [sa000058 - Arizona APOE Cohort Study](https://dss.niagads.org/studies/sa000058/) Different variants of the apolipoprotein E (APOE) gene have been associated with different levels of risk for developing Alzheimer's disease. This long-term study will gather data in cognitively normal older… [Learn more](https://dss.niagads.org/studies/sa000058/)

## Related Sample Sets

- [snd10097 - AZAPOE WGS](https://dss.niagads.org/sample-sets/snd10097/) A total of 88 samples were sequenced at USUHS using the NovaSeq platform. The FASTQ files were sent to GCAD for processing through the VCPA1.1 pipeline. All 88 samples passed… [Learn more](https://dss.niagads.org/sample-sets/snd10097/)

 ```