---
title: "Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife)"
id: "6621"
type: "cohort"
slug: "colorado-adoption-twin-study-of-lifespan-behavioral-development-cognitive-aging-catslife"
published_at: "2024-03-01T21:00:12+00:00"
modified_at: "2024-09-18T16:29:19+00:00"
url: "https://dss.niagads.org/cohorts/colorado-adoption-twin-study-of-lifespan-behavioral-development-cognitive-aging-catslife/"
markdown_url: "https://dss.niagads.org/cohorts/colorado-adoption-twin-study-of-lifespan-behavioral-development-cognitive-aging-catslife.md"
excerpt: "The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the cusp of middle adulthood, in participants from the Colorado Adoption..."
taxonomy_cohort_countries:
  - "United States of America"
---

Website:

[https://www.colorado.edu/ibg/catslife/home](https://www.colorado.edu/ibg/catslife/home)

## Description

The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the cusp of middle adulthood, in participants from the Colorado Adoption Project (CAP) and Longitudinal Twin Study (LTS) studied almost yearly from birth to early adulthood; map individual differences in growth and maintenance of cognitive abilities; evaluate and trace measured physical factors and health behaviors, biochemical markers and measured genetic pathways important to sustaining cognitive performance; and track measured environmental factors that might decrease, sustain or boost cognitive performance. (R01 AG046938 co-PI’s: Reynolds (contact), Wadsworth)

This data release includes data from 1,245 respondents who provided consent to share data and were included in a study of APOE isoforms and IQ data with up to three assessments across childhood and adolescence. [PMCID: [PMC6800620](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800620/)
]

## Related Datasets

- [NG00145 – Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife)](https://dss.niagads.org/datasets/ng00145/) The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the… [Learn more](https://dss.niagads.org/datasets/ng00145/)
- [NG00185 – DNA methylation in saliva, buffy coat and PBMC samples in CATSLife](https://dss.niagads.org/datasets/ng00185/) As part of the CATSLife project, saliva, buffy coat and peripheral blood mononuclear cells (PBMCs) were isolated from 89 CATSLife1 participants. Methylation array data were collected using Illumina EPIC methylation… [Learn more](https://dss.niagads.org/datasets/ng00185/)
- [NG00187 – Stability of general cognitive ability from infancy to adulthood: A combined twin and genomic investigation – Gustavson et al., 2025](https://dss.niagads.org/datasets/ng00187/) The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the… [Learn more](https://dss.niagads.org/datasets/ng00187/)

## Related Studies

- [sa000046 - Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife)](https://dss.niagads.org/studies/sa000046/) The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the… [Learn more](https://dss.niagads.org/studies/sa000046/)

## Related Sample Sets

- [snd10078 - CATSLife APOE](https://dss.niagads.org/sample-sets/snd10078/) This data release includes data from 1,245 respondents who provided consent to share data and were included in a study of APOE isoforms and IQ data with up to three… [Learn more](https://dss.niagads.org/sample-sets/snd10078/)
- [snd10136 - Stability of general cognitive ability from infancy to adulthood: A combined twin and genomic investigation](https://dss.niagads.org/sample-sets/snd10136/) Analyses were based on 1,098 (552 female, 546 male) individuals who completed at least one relevant wave of the ongoing Colorado Longitudinal Twin Study (LTS). This total included 640 individuals… [Learn more](https://dss.niagads.org/sample-sets/snd10136/)
- [snd10140 - DNA methylation in saliva, buffy coat and PBMC samples in CATSLife](https://dss.niagads.org/sample-sets/snd10140/) As part of the CATSLife project, saliva, buffy coat and peripheral blood mononuclear cells (PBMCs) were isolated from 89 CATSLife1 participants. Methylation array data were collected using Illumina EPIC methylation… [Learn more](https://dss.niagads.org/sample-sets/snd10140/)

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