---
title: "Dementia in Parkinson’s Disease Cohort (PDD)"
id: "5624"
type: "cohort"
slug: "dementia-in-parkinsons-disease-cohort-pdd"
published_at: "2023-12-07T16:02:22+00:00"
modified_at: "2024-09-18T16:34:30+00:00"
url: "https://dss.niagads.org/cohorts/dementia-in-parkinsons-disease-cohort-pdd/"
markdown_url: "https://dss.niagads.org/cohorts/dementia-in-parkinsons-disease-cohort-pdd.md"
excerpt: "The Role of the endolysosomal pathway in Lewy body dementia project is a population study involving Parkinson’s disease dementia (PDD) cases that were collected for a genome-wide association study. Individuals were recruited and samples were collected by VA Puget Sound..."
taxonomy_cohort_countries:
  - "Portugal"
  - "United States of America"
---

## Description

The Role of the endolysosomal pathway in Lewy body dementia project is a population study involving Parkinson’s disease dementia (PDD) cases that were collected for a genome-wide association study. Individuals were recruited and samples were collected by VA Puget Sound and Centro Hospitalar e Universitário de Coimbra in Portugal where clinical evaluations were completed.

The American cohort of samples for this project was collected by Dr. Cyrus Zabetian and Dora Yearout at VA Puget Sound. The Portuguese cohort was collected by Dr. Ana Morgadinho. Drs. Rita Guerreiro and Jose Bras as well as Kimberly Paquette, Kaitlyn Westra, and Andrew Pyman were involved in preparing the data. This work was supported by grant funding from NIH R56 AG070857. The author(s) thank the Van Andel Institute Genomics Core (RRID:SCR_022913) (Grand Rapids, MI) for providing whole-genome genotyping facilities and services.

## Related Datasets

- [NG00154 – Dementia in Parkinson’s Disease (PDD)](https://dss.niagads.org/datasets/ng00154/) One of the most common Alzheimer’s Disease Related Dementias (ADRD) is Lewy body dementia. This umbrella term comprises two clinically distinct ADRDs: Parkinson’s disease dementia (PD-dementia) and dementia with Lewy… [Learn more](https://dss.niagads.org/datasets/ng00154/)

## Related Studies

- [sa000038 - Dementia in Parkinson’s Disease](https://dss.niagads.org/studies/sa000038/) One of the most common Alzheimer’s Disease Related Dementias (ADRD) is Lewy body dementia. This umbrella term comprises two clinically distinct ADRDs: Parkinson’s disease dementia (PD-dementia) and dementia with Lewy… [Learn more](https://dss.niagads.org/studies/sa000038/)

## Related Sample Sets

- [snd10049 - Dementia in Parkinson’s Disease (PDD)](https://dss.niagads.org/sample-sets/snd10049/) This dataset contains data from 292 subjects that were genotyped using the Infinium™ Global Screening Array-24 v3.0 BeadChip. In addition to a processed VCF file with all 292 samples, the… [Learn more](https://dss.niagads.org/sample-sets/snd10049/)

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