---
title: "Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD)"
id: "3038"
type: "cohort"
slug: "harmonized-diagnostic-assessment-of-dementia-for-the-longitudinal-aging-study-of-india-lasi-dad"
published_at: "2021-09-16T21:00:14+00:00"
modified_at: "2024-09-18T16:39:05+00:00"
url: "https://dss.niagads.org/cohorts/harmonized-diagnostic-assessment-of-dementia-for-the-longitudinal-aging-study-of-india-lasi-dad/"
markdown_url: "https://dss.niagads.org/cohorts/harmonized-diagnostic-assessment-of-dementia-for-the-longitudinal-aging-study-of-india-lasi-dad.md"
excerpt: "LASI-DAD is an in-depth study of late-life cognition and dementia. It draws a sub-sample of 4,000+ LASI respondents aged 60 and older and administers in-depth cognitive tests and informant interviews. LASI is an ongoing cohort study of 72,000 community-residing older..."
taxonomy_cohort_categories:
  - "ADSP"
taxonomy_cohort_countries:
  - "India"
---

Website:

[https://lasi-dad.org/](https://lasi-dad.org/)

## Description

LASI-DAD is an in-depth study of late-life cognition and dementia. It draws a sub-sample of 4,000+ LASI respondents aged 60 and older and administers in-depth cognitive tests and informant interviews. LASI is an ongoing cohort study of 72,000 community-residing older adults aged 45 and older and their spouses regardless of age, with an oversample of persons aged 65 and above.The study design involves following all individuals who move into institutions, although that number is expected to be very small in India. Using the Census as the sampling frame, LASI is representative of both the nation as a whole and each state and union territory. Due to administrative and linguistic considerations, the fieldwork for the main LASI unfolded in three phases, and therefore the LASI-DAD fieldwork was also carried out in phases, recruiting most respondents about 6 – 7 months after the core LASI interview.

## Related Datasets

- [NG00067 – ADSP Umbrella](https://dss.niagads.org/datasets/ng00067/) This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common… [Learn more](https://dss.niagads.org/datasets/ng00067/)
- [NG00106 – LASI-DAD GWAS and Imputation](https://dss.niagads.org/datasets/ng00106/) In 2018, 960 respondents from LASI-DAD who consented to the blood sample collection have been genotyped using Illumina Infinium genotyping platforms. The datasets being submitted include the original genotype assayed… [Learn more](https://dss.niagads.org/datasets/ng00106/)
- [NG00171 – Population Structure in LASI-DAD](https://dss.niagads.org/datasets/ng00171/) This dataset includes summary statistics characterizing genetic population structure of individuals in the LASI-DAD cohort. This includes estimates of population admixture and founder events, including segments of Neanderthal and Denisovan… [Learn more](https://dss.niagads.org/datasets/ng00171/)

## Related Studies

- [sa000019 - The Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD)](https://dss.niagads.org/studies/sa000019/) The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is an add-on study to the Longitudinal Aging Study in India (LASI) focused on late-life cognition… [Learn more](https://dss.niagads.org/studies/sa000019/)

## Related Sample Sets

- [snd10023 - LASI-DAD GWAS GSA](https://dss.niagads.org/sample-sets/snd10023/) The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is an add-on study to the Longitudinal Aging Study in India (LASI) focused on late-life cognition… [Learn more](https://dss.niagads.org/sample-sets/snd10023/)
- [snd10033 - LASI-DAD WGS](https://dss.niagads.org/sample-sets/snd10033/) 2,768 LASI-DAD respondents from 18 diverse ethno-linguistic and genographic groups across India who consented to the blood sample collection samples were sequenced at Medgenome on the HiSeqX machine. FASTQ files… [Learn more](https://dss.niagads.org/sample-sets/snd10033/)
- [snd10117 - Population Structure in LASI-DAD](https://dss.niagads.org/sample-sets/snd10117/) A total of 2,762 LASI-DAD participants, including 22 trios (mother-father-child), were sequenced at MedGenome, Inc. (Bangalore, India) at an average read depth of 30. Individuals were sampled from 18 different… [Learn more](https://dss.niagads.org/sample-sets/snd10117/)

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