---
title: "Massachusetts Alzheimer’s Disease Research Center (MassADRC)"
id: "3582"
type: "cohort"
slug: "massachusetts-alzheimers-disease-research-center"
published_at: "2022-05-11T15:59:25+00:00"
modified_at: "2024-09-18T16:59:06+00:00"
url: "https://dss.niagads.org/cohorts/massachusetts-alzheimers-disease-research-center/"
markdown_url: "https://dss.niagads.org/cohorts/massachusetts-alzheimers-disease-research-center.md"
excerpt: "The Massachusetts Alzheimer’s Disease Research Center (MADRC) is a P30 research center funded by the National Institute on Aging. Our center has been at the forefront of dementia research, treatment and care since 1984.Our expert staff from both Mass General..."
taxonomy_cohort_countries:
  - "United States of America"
---

Website:

[https://www.madrc.org/](https://www.madrc.org/)

## Description

The Massachusetts Alzheimer’s Disease Research Center (MADRC) is a P30 research center funded by the National Institute on Aging. Our center has been at the forefront of dementia research, treatment and care since 1984.  
Our expert staff from both Mass General Hospital and Brigham and Women’s Hospital work closely together under the MADRC umbrella to lead cutting-edge research as well as to provide both professional and community resources and education. Our goal is to find effective treatments and eventually a cure for Alzheimer’s disease and related dementias.

## Related Datasets

- [NG00121 – Alzheimer’s disease single-neuron whole-genome sequencing – Miller 2022](https://dss.niagads.org/datasets/ng00121/) Single-neuron amplified genome libraries were sequenced (WGS) on Illumina instruments and aligned to the human reference genome GRCh37. Linked-read analysis (LiRA) and SCAN-SNV were used to identify single-cell somatic mutations.… [Learn more](https://dss.niagads.org/datasets/ng00121/)

## Related Studies

- [sa000022 - Alzheimer’s disease single-neuron whole-genome sequencing – Miller 2022](https://dss.niagads.org/studies/sa000022/) This study performed whole-genome sequencing of single neurons isolated from prefrontal cortex (PFC) and hippocampus CA1 (HC) of postmortem human brain of individuals with Alzheimer’s disease (AD)(Braak stage V-VI) or… [Learn more](https://dss.niagads.org/studies/sa000022/)

## Related Sample Sets

- [snd10029 - Alzheimer’s disease single-neuron whole-genome sequencing – Miller 2022](https://dss.niagads.org/sample-sets/snd10029/) This study performed whole-genome sequencing of single neurons isolated from prefrontal cortex (PFC) and hippocampus CA1 (HC) of postmortem human brain of individuals with Alzheimer’s disease (AD) (Braak stage V-VI)… [Learn more](https://dss.niagads.org/sample-sets/snd10029/)

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