---
title: "Mexican Health and Aging Study (MHAS)"
id: "3832"
type: "cohort"
slug: "mexican-health-and-aging-study-mhas"
published_at: "2022-09-16T13:40:57+00:00"
modified_at: "2024-09-18T17:07:57+00:00"
url: "https://dss.niagads.org/cohorts/mexican-health-and-aging-study-mhas/"
markdown_url: "https://dss.niagads.org/cohorts/mexican-health-and-aging-study-mhas.md"
excerpt: "The Mexican Health and Aging Study (MHAS) is a national longitudinal study of adults 50 years and older in Mexico. The baseline survey, with national and urban/rural representation of adults born in 1951 or earlier, was conducted in 2001 with..."
taxonomy_cohort_categories:
  - "ADSP"
taxonomy_cohort_countries:
  - "Mexico"
---

Website:

[http://www.mhasweb.org/index.aspx](http://www.mhasweb.org/index.aspx)

## Description

[The Mexican Health and Aging Study (MHAS)](http://www.mhasweb.org/index.aspx)
 is a national longitudinal study of adults 50 years and older in Mexico.

The baseline survey, with national and urban/rural representation of adults born in 1951 or earlier, was conducted in 2001 with follow-up interviews in 2003, 2012, 2015, and 2018. A new sample of adults born between 1952-1962 was added in 2012. Similarly, in 2018 a new cohort of adults born between 1963 and 1968 was added to refresh the sample.

The study is a collaborative effort among researchers from the University of Texas Medical Branch (UTMB), the Instituto Nacional de Estadística y Geografía (INEGI, Mexico), the University of Wisconsin, the Instituto Nacional de Geriatría (INGER, Mexico), the Instituto Nacional de Salud Pública (INSP, Mexico), and University of California Los Angeles (UCLA). The MHAS is partly supported by the National Institutes of Health/National Institute on Aging (R01AG018016, R Wong, PI) in the United States and the Instituto Nacional de Estadística y Geografía (INEGI) in Mexico.

Cohort description taken from the [MHAS website](http://www.mhasweb.org/index.aspx)
, July 29, 2022.

## Related Datasets

- [NG00067 – ADSP Umbrella](https://dss.niagads.org/datasets/ng00067/) This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common… [Learn more](https://dss.niagads.org/datasets/ng00067/)
- [NG00196- Genotyping short tandem repeats using the ADSP R4 cohort](https://dss.niagads.org/datasets/ng00196/) A two-step pipeline was used to first identify expanded short tandem repeats (STRs) in ADSP samples using ExpansionHunter Denovo and then genotype the identified STRs, along with additional polymorphic STRs… [Learn more](https://dss.niagads.org/datasets/ng00196/)

## Related Studies

- [sa000001 - Alzheimer’s Disease Sequencing Project (ADSP)](https://dss.niagads.org/studies/sa000001/) Background An initiative in response to the National Alzheimer’s Project Act (NAPA) has been working towards new biological insights and cures for Alzheimer’s Disease (AD) since its introduction by NIH… [Learn more](https://dss.niagads.org/studies/sa000001/)
- [sa000087 - Genotyping short tandem repeats using ADSP R4](https://dss.niagads.org/studies/sa000087/) Variation in tandem repeats (TRs), particularly large expansions of triplet repeats (e.g., polyCAG), is known to cause a number of late-onset neurological diseases. Due to their repetitive and degenerate nature,… [Learn more](https://dss.niagads.org/studies/sa000087/)

## Related Sample Sets

- [snd10031 - ADSP-FUS2 WGS](https://dss.niagads.org/sample-sets/snd10031/) The ADSP-FUS is a National Institute on Aging (NIA) initiative focused on identifying genetic risk and protective variants for late-onset Alzheimer Disease (LOAD). A concern in AD genetic studies is… [Learn more](https://dss.niagads.org/sample-sets/snd10031/)
- [snd10147 - ADSP R4 Short Tandem Repeats (STRs)](https://dss.niagads.org/sample-sets/snd10147/) This dataset comprises short tandem repeat (STR) genotypes from 31,681 whole-genome sequencing (WGS) samples from the ADSP R4 data release. The STRs were genotyped using ExpansionHunter with a custom catalog… [Learn more](https://dss.niagads.org/sample-sets/snd10147/)

 ```
