---
title: "Microglia Genomic Atlas – Neuropathology Brain Bank at Mount Sinai Hospital (MiGA MSSM)"
id: "2851"
type: "cohort"
slug: "miga-mssm"
published_at: "2021-06-30T14:40:18+00:00"
modified_at: "2024-09-18T17:11:43+00:00"
url: "https://dss.niagads.org/cohorts/miga-mssm/"
markdown_url: "https://dss.niagads.org/cohorts/miga-mssm.md"
excerpt: "Research conducted using human post-mortem brain tissue remains a critical component of translational brain research programs. To meet the urgent need for this precious resource, the Neuropathology Brain Bank and Research CoRE was launched as part of the Mount Sinai..."
taxonomy_cohort_countries:
  - "United States of America"
---

Website:

[https://icahn.mssm.edu/research/portal/resources/deans-cores/neuropathology](https://icahn.mssm.edu/research/portal/resources/deans-cores/neuropathology)

## Description

Research conducted using human post-mortem brain tissue remains a critical component of translational brain research programs. To meet the urgent need for this precious resource, the Neuropathology Brain Bank and Research CoRE was launched as part of the Mount Sinai Strategic Plan in July 2018.  
The neuropathology brain bank is focused on collecting and distributing high quality fresh frozen and fixed human brain tissues to researchers. The goal of the new brain bank is to expand brain collections in targeted areas, including neurodegenerative disease, neuropsychiatric disease, aging, and others. This collection will supplement existing collections and deploy modern banking protocols, including advance inventory management (i.e., parcellation and bar-coding), digital microscopy, machine learning-based assessments, and other state-of-the-art approaches. These protocols will greatly facilitate access to tissue. However, being a new collection with limited but expanding inventory, we are also dedicated to assisting researchers interface with the brain collections inside and outside Mount Sinai to gain access.   
The Brain Bank provides a flexible tissue repository platform to facilitate collection, characterization and distribution of tissues and data for clinical and translational research projects with a neuropathology component.

## Related Datasets

- [NG00105 – MiGA – Microglia Genomic Atlas](https://dss.niagads.org/datasets/ng00105/) Microglia Genomic Atlas – MiGA (NG00105.v1): Post-mortem brain samples were obtained from the Netherlands Brain Bank (NBB). The permission to collect human brain material was obtained from the Ethical Committee… [Learn more](https://dss.niagads.org/datasets/ng00105/)

## Related Studies

- [sa000018 - MiGA – Microglia Genomic Atlas](https://dss.niagads.org/studies/sa000018/) Human post-mortem brain samples were obtained from the Netherlands Brain Bank (NBB) and the Neuropathology Brain Bank and Research CoRE at Mount Sinai Hospital. The permission to collect human brain… [Learn more](https://dss.niagads.org/studies/sa000018/)

## Related Sample Sets

- [snd10022 - MiGA – Microglia Genomic Atlas](https://dss.niagads.org/sample-sets/snd10022/) The Microglia Genomic Atlas (MiGA) is a genetic and transcriptomic resource comprised of 255 primary human microglia samples isolated ex vivo from four different brain regions of 100 human subjects… [Learn more](https://dss.niagads.org/sample-sets/snd10022/)
- [snd10082 - MiGASTi – Microglia Genomic Atlas after Stimulation](https://dss.niagads.org/sample-sets/snd10082/) MiGASTi is an atlas of human microglia gene expression following cell culture and exposure to a range of inflammatory stimulations. Post-mortem brain samples were obtained from the Netherlands Brain Bank… [Learn more](https://dss.niagads.org/sample-sets/snd10082/)

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