---
title: "Puerto Rican Alzheimer’s Disease Initiative (PRADI)"
id: "3852"
type: "cohort"
slug: "puerto-rican-alzheimers-disease-initiative-pradi"
published_at: "2022-09-22T19:42:29+00:00"
modified_at: "2024-09-18T17:55:45+00:00"
url: "https://dss.niagads.org/cohorts/puerto-rican-alzheimers-disease-initiative-pradi/"
markdown_url: "https://dss.niagads.org/cohorts/puerto-rican-alzheimers-disease-initiative-pradi.md"
excerpt: "The Puerto Rican Alzheimer’s Disease Initiative (PRADI) is a NIH NIA study of late-onset Alzheimer disease focused on the Caribbean-Hispanic Puerto Rican population. Participants were ascertained for an AD/ADRD Memory Study, including healthy controls. Eligibility was based on self-reported Puerto..."
taxonomy_cohort_categories:
  - "ADSP"
taxonomy_cohort_countries:
  - "Puerto Rico"
---

## Description

The **Puerto Rican Alzheimer’s Disease Initiative (PRADI)** is a NIH NIA study of late-onset Alzheimer disease focused on the Caribbean-Hispanic Puerto Rican population. Participants were ascertained for an AD/ADRD Memory Study, including healthy controls. Eligibility was based on self-reported Puerto Rican heritage. Most participants were recruited in the Island of Puerto Rico with a small fraction being ascertained in South Florida, New York, and Connecticut.

Participants were ascertained and evaluated through community centers, private memory clinics and adult day care centers. Some participants were evaluated in their homes. All participants greater than 60 years of age underwent a standard clinical evaluation consisting of a medical and family history interview, neuropsychological testing, behavioral and emotional assessments, and functional measures. Venous blood samples (or saliva samples when needed) were collected on all participants. All assessments were conducted in the preferred language of the participant or knowledgeable informant.

## Related Datasets

- [NG00067 – ADSP Umbrella](https://dss.niagads.org/datasets/ng00067/) This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common… [Learn more](https://dss.niagads.org/datasets/ng00067/)

## Related Studies

- [sa000001 - Alzheimer’s Disease Sequencing Project (ADSP)](https://dss.niagads.org/studies/sa000001/) Background An initiative in response to the National Alzheimer’s Project Act (NAPA) has been working towards new biological insights and cures for Alzheimer’s Disease (AD) since its introduction by NIH… [Learn more](https://dss.niagads.org/studies/sa000001/)

## Related Sample Sets

- [snd10031 - ADSP-FUS2 WGS](https://dss.niagads.org/sample-sets/snd10031/) The ADSP-FUS is a National Institute on Aging (NIA) initiative focused on identifying genetic risk and protective variants for late-onset Alzheimer Disease (LOAD). A concern in AD genetic studies is… [Learn more](https://dss.niagads.org/sample-sets/snd10031/)

 ```