---
title: "ADGC AA WES"
id: "1616"
type: "sample_set"
slug: "snd10003"
published_at: "2020-02-19T18:48:47+00:00"
modified_at: "2023-12-14T22:23:22+00:00"
url: "https://dss.niagads.org/sample-sets/snd10003/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10003.md"
excerpt: "ADGC African American samples were sequenced at University of Miami on the HiSeq3000 machine. 3226 samples were sequenced using the Agilent WES v6 target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1..."
---

## Description

ADGC African American samples were sequenced at University of Miami on the HiSeq3000 machine. 3226 samples were sequenced using the Agilent WES v6 target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 2763 passed sequencing metrics and quality control.

## Cohorts

- [Genetic and Environmental Risk Factors for Alzheimer’s Disease Among African Americans (GenerAAtions)](https://dss.niagads.org/cohorts/genetic-and-environmental-risk-factors-for-alzheimers-disease-among-african-americans-generaations/)
- [Minority Aging Research Study (MARS)](https://dss.niagads.org/cohorts/minority-aging-research-study-mars/)
- [Multi-Institutional Research in Alzheimer's Genetic Epidemiology (MIRAGE)](https://dss.niagads.org/cohorts/multi-institutional-research-in-alzheimers-genetic-epidemiology-mirage/)
- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)
- [Religious Orders Study/Memory and Aging Project (ROSMAP)](https://dss.niagads.org/cohorts/religious-orders-study-memory-and-aging-project-rosmap/)
- [University of Miami (MIA)](https://dss.niagads.org/cohorts/university-of-miami-mia/)
- [Vanderbilt University (VAN)](https://dss.niagads.org/cohorts/vanderbilt-university-van/)

## Sex

### Total number of samples: 3,158

Female2,25671.4 %

Male90228.6 %

## Race

### Total number of samples: 3,158

| Black or African American | 3,155 |
| --- | --- |
| White | 3 |

## Ethnicity

### Total number of samples: 3,158

Not Hispanic or Latino

3,118

98.7%

Hispanic or Latino

4

0.1%

Not Applicable/Not Available

36

1.1%

## Diagnosis

### Total number of samples: 3,158

| AD |  |  |
| --- | --- | --- |
| Control | 1,556 | 49.3% |
| Case | 1,170 | 37.0% |
| Other | 1 | 0.0% |
| Unknown | 431 | 13.6% |

## APOE

### Total number of samples: 3,158

- 2225 (0.8%)
- 23365 (11.6%)
- 24164 (5.2%)
- 331,209 (38.3%)
- 341,122 (35.5%)
- 44261 (8.3%)
- NA12 (0.4%)