---
title: "FASe_Families WGS"
id: "2424"
type: "sample_set"
slug: "snd10018"
published_at: "2021-02-24T01:30:59+00:00"
modified_at: "2023-12-14T22:30:17+00:00"
url: "https://dss.niagads.org/sample-sets/snd10018/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10018.md"
excerpt: "FASe_WGS samples were whole-genome sequenced at Broad either on the HiSeqX or HiSeq2000/2500 machine. Samples in either format (BAM files from hg37 build and FASTQ files) were sent to GCAD for processing on the VCPA1.1 pipeline. 91 samples passed sequencing..."
---

## Description

FASe_WGS samples were whole-genome sequenced at Broad either on the HiSeqX or HiSeq2000/2500 machine. Samples in either format (BAM files from hg37 build and FASTQ files) were sent to GCAD for processing on the VCPA1.1 pipeline. 91 samples passed sequencing metrics and quality control.

## Cohorts

- [National Centralized Repository for Alzheimer’s Disease and Related Dementias Family (NCRAD Family)](https://dss.niagads.org/cohorts/national-centralized-repository-for-alzheimers-disease-and-related-dementias-family-ncrad-family/)
- [National Institute of Aging Alzheimer’s Disease Family Based Study (NIA AD-FBS)](https://dss.niagads.org/cohorts/national-institute-on-aging-late-onset-of-alzheimers-disease-family-nia-load/)
- [University of Washington Families (RAS)](https://dss.niagads.org/cohorts/university-of-washington-families-ras/)

## Sex

### Total number of samples: 91

Female5661.5 %

Male3538.5 %

## Race

### Total number of samples: 91

| American Indian/Alaska Native | 3 |
| --- | --- |
| White | 88 |

## Ethnicity

### Total number of samples: 91

Not Hispanic or Latino

90

98.9%

Hispanic or Latino

1

1.1%

## Diagnosis

### Total number of samples: 91

| AD |  |  |
| --- | --- | --- |
| Control | 13 | 14.3% |
| Case | 74 | 81.3% |
| Other | 1 | 1.1% |
| Unknown | 3 | 3.3% |

## APOE

### Total number of samples: 91

- 235 (5.5%)
- 338 (8.8%)
- 3433 (36.3%)
- 4445 (49.5%)