---
title: "KnightADRC WGS"
id: "2427"
type: "sample_set"
slug: "snd10019"
published_at: "2021-02-24T01:32:27+00:00"
modified_at: "2023-12-14T22:30:28+00:00"
url: "https://dss.niagads.org/sample-sets/snd10019/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10019.md"
excerpt: "Knight ADRC samples were whole-genome sequenced at Broad/Genentech either on the HiSeqX or HiSeq2000/2500 machine. Samples in either format (BAM files from hg37 build and FASTQ files) were sent to GCAD for processing on the VCPA1.1 pipeline. 77 samples passed..."
---

## Description

Knight ADRC samples were whole-genome sequenced at Broad/Genentech either on the HiSeqX or HiSeq2000/2500 machine. Samples in either format (BAM files from hg37 build and FASTQ files) were sent to GCAD for processing on the VCPA1.1 pipeline. 77 samples passed sequencing metrics and quality control.

## Cohorts

- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)

## Sex

### Total number of samples: 77

Female4558.4 %

Male3241.6 %

## Race

### Total number of samples: 77

| Native Hawaiian or Other Pacific Islander | 1 |
| --- | --- |
| Black or African American | 5 |
| White | 71 |

## Ethnicity

### Total number of samples: 77

Not Hispanic or Latino

75

97.4%

Hispanic or Latino

1

1.3%

Not Applicable/Not Available

1

1.3%

## Diagnosis

### Total number of samples: 77

| AD |  |  |
| --- | --- | --- |
| Control | 14 | 18.2% |
| Case | 54 | 70.1% |
| Unknown | 9 | 11.7% |

## APOE

### Total number of samples: 77

- 231 (1.3%)
- 3453 (68.8%)
- 4423 (29.9%)