---
title: "Microglia expression profiles in AD"
id: "2741"
type: "sample_set"
slug: "snd10021"
published_at: "2021-06-01T16:35:27+00:00"
modified_at: "2021-06-17T17:58:44+00:00"
url: "https://dss.niagads.org/sample-sets/snd10021/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10021.md"
excerpt: "The microglia profile of the Parietal lobe of 44 donors from the Knight ADRC were sequenced using 10X genomics 3’ Chemistry v3 (10,000 nuclei per donor, 50,000 reads per nuclei), and aligned to the precursor mRNA reference (build GRCh38)"
---

## Description

The microglia profile of the Parietal lobe of 44 donors from the Knight ADRC were sequenced using 10X genomics 3’ Chemistry v3 (10,000 nuclei per donor, 50,000 reads per nuclei), and aligned to the precursor mRNA reference (build GRCh38)

## Cohorts

- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)

## Sex

### Total number of samples: 44

Female2659.1 %

Male1840.9 %

## Diagnosis

### Total number of samples: 44

| Alzheimer's Disease and Related Dementias (ADRD) |  |  |
| --- | --- | --- |
| Control | 5 | 11.4% |
| Case | 29 | 65.9% |
| Other | 10 | 22.7% |

## APOE

### Total number of samples: 44

- 231 (2.3%)
- 242 (4.5%)
- 3324 (54.5%)
- 3415 (34.1%)
- 442 (4.5%)