---
title: "EOAD1 WGS"
id: "3815"
type: "sample_set"
slug: "snd10032"
published_at: "2022-09-15T13:09:26+00:00"
modified_at: "2023-12-14T22:31:40+00:00"
url: "https://dss.niagads.org/sample-sets/snd10032/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10032.md"
excerpt: "The EOAD samples were sequenced at USUHS on the NovaSeq machine. 3176 samples were sequenced and FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 3,132 samples passed sequencing metrics and quality control..."
---

## Description

The EOAD samples were sequenced at USUHS on the NovaSeq machine. 3176 samples were sequenced and FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 3,132 samples passed sequencing metrics and quality control checks.

## Cohorts

- [Adult Changes in Thought (ACT)](https://dss.niagads.org/cohorts/adult-changes-in-thought-act/)
- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)
- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 3,131

Female1,77356.6 %

Male1,35843.4 %

## Race

### Total number of samples: 3,131

| American Indian/Alaska Native | 29 |
| --- | --- |
| Asian | 57 |
| Black or African American | 210 |
| White | 2,754 |
| Other | 75 |
| NA | 6 |

## Ethnicity

### Total number of samples: 3,131

Not Hispanic or Latino

2,501

79.9%

Hispanic or Latino

298

9.5%

Not Applicable/Not Available

332

10.6%

## Diagnosis

### Total number of samples: 3,131

| AD |  |  |
| --- | --- | --- |
| Control | 719 | 23.0% |
| Case | 1,612 | 51.5% |
| Unknown | 800 | 25.6% |

## APOE

### Total number of samples: 3,131

- 2214 (0.4%)
- 23296 (9.5%)
- 2470 (2.2%)
- 331,204 (38.5%)
- 341,172 (37.4%)
- 44355 (11.3%)
- NA20 (0.6%)