---
title: "LASI-DAD WGS"
id: "3864"
type: "sample_set"
slug: "snd10033"
published_at: "2022-09-15T19:18:13+00:00"
modified_at: "2023-12-14T22:31:54+00:00"
url: "https://dss.niagads.org/sample-sets/snd10033/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10033.md"
excerpt: "2,768 LASI-DAD respondents from 18 diverse ethno-linguistic and genographic groups across India who consented to the blood sample collection samples were sequenced at Medgenome on the HiSeqX machine. FASTQ files were sent to GCAD for processing on the VCPA 1.1..."
---

## Description

2,768 LASI-DAD respondents from 18 diverse ethno-linguistic and genographic groups across India who consented to the blood sample collection samples were sequenced at Medgenome on the HiSeqX machine. FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 2,686 samples passed sequencing metrics and quality control checks (including 6 technical replicates sequenced with ADSP rounds).

## Cohorts

- [Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)](https://dss.niagads.org/cohorts/estudio-familiar-de-influencia-genetica-en-alzheimer-efiga/)
- [Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD)](https://dss.niagads.org/cohorts/harmonized-diagnostic-assessment-of-dementia-for-the-longitudinal-aging-study-of-india-lasi-dad/)
- [National Centralized Repository for Alzheimer’s Disease and Related Dementias Family (NCRAD Family)](https://dss.niagads.org/cohorts/national-centralized-repository-for-alzheimers-disease-and-related-dementias-family-ncrad-family/)

## Sex

### Total number of samples: 2,686

Female1,41352.6 %

Male1,27347.4 %

## Race

### Total number of samples: 2,686

| Asian | 2,682 |
| --- | --- |
| Black or African American | 1 |
| Other | 3 |

## Ethnicity

### Total number of samples: 2,686

Not Hispanic or Latino

2,683

99.9%

Hispanic or Latino

3

0.1%

## Diagnosis

### Total number of samples: 2,686

| AD |  |  |
| --- | --- | --- |
| Control | 2,495 | 92.9% |
| Case | 3 | 0.1% |
| Unknown | 188 | 7.0% |

## APOE

### Total number of samples: 2,686

- 231 (0.0%)
- 331 (0.0%)
- 342 (0.1%)
- NA2,682 (99.9%)