---
title: "ADGC ADC Round 3"
id: "6447"
type: "sample_set"
slug: "snd10060"
published_at: "2024-02-07T21:52:44+00:00"
modified_at: "2024-02-07T21:52:45+00:00"
url: "https://dss.niagads.org/sample-sets/snd10060/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10060.md"
excerpt: "The ADC3 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_A) BeadChip which captures genotype data on 733,202 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC)..."
---

## Description

The ADC3 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_A) BeadChip which captures genotype data on 733,202 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)
- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)
- [University of Toronto (TOR)](https://dss.niagads.org/cohorts/university-of-toronto/)
- [University of Washington Families (RAS)](https://dss.niagads.org/cohorts/university-of-washington-families-ras/)

## Sex

### Total number of samples: 2,040

Female1,13855.8 %

Male75937.2 %

Sex not reported: 143

## Race

### Total number of samples: 2,040

| Black or African American | 260 |
| --- | --- |
| White | 1,103 |
| Other | 1 |
| NA | 676 |

## Ethnicity

### Total number of samples: 2,040

Not Hispanic or Latino

1,343

65.8%

Hispanic or Latino

16

0.8%

Not Applicable/Not Available

681

33.4%

## Diagnosis

### Total number of samples: 2,040

| AD |  |  |
| --- | --- | --- |
| Control | 491 | 24.1% |
| Case | 634 | 31.1% |
| Unknown | 915 | 44.9% |

## APOE

### Total number of samples: 2,040

- 2210 (0.5%)
- 23136 (6.7%)
- 2459 (2.9%)
- 33785 (38.5%)
- 34649 (31.8%)
- 44157 (7.7%)
- NA244 (12.0%)