---
title: "ADGC ADC Round 4"
id: "6449"
type: "sample_set"
slug: "snd10061"
published_at: "2024-02-07T21:54:45+00:00"
modified_at: "2024-02-07T21:54:46+00:00"
url: "https://dss.niagads.org/sample-sets/snd10061/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10061.md"
excerpt: "The ADC4 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_H) BeadChip which captures genotype data on 730,525 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC)..."
---

## Description

The ADC4 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_H) BeadChip which captures genotype data on 730,525 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 1,054

Female60357.2 %

Male45142.8 %

## Race

### Total number of samples: 1,054

| Black or African American | 6 |
| --- | --- |
| White | 1,043 |
| Other | 5 |

## Ethnicity

### Total number of samples: 1,054

Not Hispanic or Latino

1,042

98.9%

Hispanic or Latino

11

1.0%

Not Applicable/Not Available

1

0.1%

## Diagnosis

### Total number of samples: 1,054

| AD |  |  |
| --- | --- | --- |
| Control | 352 | 33.4% |
| Case | 375 | 35.6% |
| Unknown | 327 | 31.0% |

## APOE

### Total number of samples: 1,054

- 225 (0.5%)
- 23100 (9.5%)
- 2428 (2.7%)
- 33522 (49.5%)
- 34323 (30.6%)
- 4471 (6.7%)
- NA5 (0.5%)