---
title: "ADGC ADC Round 5"
id: "6451"
type: "sample_set"
slug: "snd10062"
published_at: "2024-02-07T21:56:05+00:00"
modified_at: "2024-02-07T21:56:06+00:00"
url: "https://dss.niagads.org/sample-sets/snd10062/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10062.md"
excerpt: "The ADC5 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_H) BeadChip which captures genotype data on 730,525 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC)..."
---

## Description

The ADC5 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Human OmniExpress (HumanOmniExpress-12v1_H) BeadChip which captures genotype data on 730,525 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 1,222

Female71458.4 %

Male50741.5 %

Sex not reported: 1

## Race

### Total number of samples: 1,222

| White | 1,221 |
| --- | --- |
| NA | 1 |

## Ethnicity

### Total number of samples: 1,222

Not Hispanic or Latino

1,220

99.8%

Not Applicable/Not Available

2

0.2%

## Diagnosis

### Total number of samples: 1,222

| AD |  |  |
| --- | --- | --- |
| Control | 456 | 37.3% |
| Case | 354 | 29.0% |
| Unknown | 412 | 33.7% |

## APOE

### Total number of samples: 1,222

- 224 (0.3%)
- 23127 (10.4%)
- 2436 (2.9%)
- 33627 (51.3%)
- 34358 (29.3%)
- 4466 (5.4%)
- NA4 (0.3%)