---
title: "ADGC ADC Round 12"
id: "5923"
type: "sample_set"
slug: "snd10069"
published_at: "2024-02-07T19:22:49+00:00"
modified_at: "2024-02-07T19:22:50+00:00"
url: "https://dss.niagads.org/sample-sets/snd10069/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10069.md"
excerpt: "The ADC12 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium GSAMD-24v2-0_20024620_A1 BeadChip which captures genotype data on 759,993 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality..."
---

## Description

The ADC12 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium GSAMD-24v2-0_20024620_A1 BeadChip which captures genotype data on 759,993 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 1,320

Female74056.1 %

Male57943.9 %

Sex not reported: 1

## Race

### Total number of samples: 1,320

| American Indian/Alaska Native | 3 |
| --- | --- |
| Asian | 41 |
| Native Hawaiian or Other Pacific Islander | 2 |
| Black or African American | 105 |
| White | 1,148 |
| Other | 19 |
| NA | 2 |

## Ethnicity

### Total number of samples: 1,320

Not Hispanic or Latino

1,203

91.1%

Hispanic or Latino

108

8.2%

Not Applicable/Not Available

9

0.7%

## Diagnosis

### Total number of samples: 1,320

| AD |  |  |
| --- | --- | --- |
| Control | 384 | 29.1% |
| Case | 284 | 21.5% |
| Unknown | 652 | 49.4% |

## APOE

### Total number of samples: 1,320

- 2213 (1.0%)
- 23123 (9.3%)
- 2428 (2.1%)
- 33629 (47.7%)
- 34435 (33.0%)
- 4492 (7.0%)