---
title: "ADGC ADC Round 14"
id: "5762"
type: "sample_set"
slug: "snd10071"
published_at: "2024-02-07T19:37:44+00:00"
modified_at: "2024-02-07T19:37:45+00:00"
url: "https://dss.niagads.org/sample-sets/snd10071/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10071.md"
excerpt: "Sample selection and genotyping was coordinated and paid for by the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD). NCRAD supported genotyping of samples from subjects with diagnoses other than AD, MCI, or cognitively normal. The ADC14 sample..."
---

## Description

Sample selection and genotyping was coordinated and paid for by the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD). NCRAD supported genotyping of samples from subjects with diagnoses other than AD, MCI, or cognitively normal. The ADC14 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium Global Screening Array (GSAMD-24v2-0_20024620_A1) BeadChip which captures genotype data on 759,993 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 4,620

Female2,29049.6 %

Male2,33050.4 %

## Race

### Total number of samples: 4,620

| American Indian/Alaska Native | 5 |
| --- | --- |
| Asian | 139 |
| Native Hawaiian or Other Pacific Islander | 2 |
| Black or African American | 480 |
| White | 3,900 |
| Other | 94 |

## Ethnicity

### Total number of samples: 4,620

Not Hispanic or Latino

4,264

92.3%

Hispanic or Latino

336

7.3%

Not Applicable/Not Available

20

0.4%

## Diagnosis

### Total number of samples: 4,620

| AD |  |  |
| --- | --- | --- |
| Control | 430 | 9.3% |
| Case | 225 | 4.9% |
| Unknown | 3,965 | 85.8% |

## APOE

### Total number of samples: 4,620

- 2221 (0.5%)
- 23469 (10.2%)
- 2495 (2.1%)
- 332,525 (54.7%)
- 341,283 (27.8%)
- 44226 (4.9%)
- NA1 (0.0%)