---
title: "ADGC ADC Round 15"
id: "5765"
type: "sample_set"
slug: "snd10072"
published_at: "2024-02-07T19:37:58+00:00"
modified_at: "2024-02-07T19:37:59+00:00"
url: "https://dss.niagads.org/sample-sets/snd10072/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10072.md"
excerpt: "Sample selection and genotyping was coordinated and paid for by the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD). NCRAD supported genotyping of samples from subjects with diagnoses other than AD, MCI, or cognitively normal. The ADC15 sample..."
---

## Description

Sample selection and genotyping was coordinated and paid for by the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD). NCRAD supported genotyping of samples from subjects with diagnoses other than AD, MCI, or cognitively normal. The ADC15 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium Global Screening Array (GSA-24v3-0_A1) BeadChip which captures genotype data on 654,027 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.

## Cohorts

- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)

## Sex

### Total number of samples: 894

Female55161.6 %

Male34338.4 %

## Race

### Total number of samples: 894

| American Indian/Alaska Native | 1 |
| --- | --- |
| Asian | 37 |
| Native Hawaiian or Other Pacific Islander | 1 |
| Black or African American | 107 |
| White | 731 |
| Other | 7 |
| NA | 10 |

## Ethnicity

### Total number of samples: 894

Not Hispanic or Latino

826

92.4%

Hispanic or Latino

55

6.2%

Not Applicable/Not Available

13

1.5%

## Diagnosis

### Total number of samples: 894

| AD |  |  |
| --- | --- | --- |
| Control | 620 | 69.4% |
| Case | 17 | 1.9% |
| Unknown | 257 | 28.7% |

## APOE

### Total number of samples: 894

- 228 (0.9%)
- 2376 (8.5%)
- 2421 (2.3%)
- 33459 (51.3%)
- 34272 (30.4%)
- 4458 (6.5%)