---
title: "MiGASTi – Microglia Genomic Atlas after Stimulation"
id: "6788"
type: "sample_set"
slug: "snd10082"
published_at: "2024-05-06T19:10:22+00:00"
modified_at: "2024-05-06T19:10:23+00:00"
url: "https://dss.niagads.org/sample-sets/snd10082/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10082.md"
excerpt: "MiGASTi is an atlas of human microglia gene expression following cell culture and exposure to a range of inflammatory stimulations. Post-mortem brain samples were obtained from the Netherlands Brain Bank (NBB). The permission to collect human brain material was obtained..."
---

## Description

MiGASTi is an atlas of human microglia gene expression following cell culture and exposure to a range of inflammatory stimulations.

Post-mortem brain samples were obtained from the Netherlands Brain Bank (NBB). The permission to collect human brain material was obtained from the Ethical Committee of the VU University Medical Center, Amsterdam, The Netherlands. Informed consent for autopsy, the use of brain tissue and accompanied clinical information for research purposes was obtained per donor ante-mortem. Neuropathological assessments have been performed by the NBB. Detailed information per donor, including tissue type, age, sex, postmortem interval, pH of cerebrospinal fluid, cause of death, diagnosis, use of medication and neuropathological information is provided.

## Cohorts

- [Microglia Genomic Atlas - Netherlands Brain Bank (MiGA NBB)](https://dss.niagads.org/cohorts/miga-nbb/)
- [Microglia Genomic Atlas - Neuropathology Brain Bank at Mount Sinai Hospital (MiGA MSSM)](https://dss.niagads.org/cohorts/miga-mssm/)

## Sex

### Total number of samples: 934

Female45849.0 %

Male47651.0 %

## Race

### Total number of samples: 954

| White | 772 |
| --- | --- |
| NA | 182 |

## Diagnosis

### Total number of samples: 1,066

| Neurological and Psychiatric Brain Disorders |  |  |
| --- | --- | --- |
| Control | 422 | 39.6% |
| Case | 644 | 60.4% |

## APOE

### Total number of samples: 870

- 2398 (11.3%)
- 2422 (2.5%)
- 33328 (37.7%)
- 34120 (13.8%)
- 4412 (1.4%)
- NA278 (32.0%)
- 12 (1.4%)