---
title: "EOAD2 WGS"
id: "7355"
type: "sample_set"
slug: "snd10095"
published_at: "2024-11-27T16:02:24+00:00"
modified_at: "2024-11-27T16:02:25+00:00"
url: "https://dss.niagads.org/sample-sets/snd10095/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10095.md"
excerpt: "1,264 samples were sequenced at USUHS on the NovaSeq machine. FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 1,183 samples passed sequencing metrics and quality control checks."
---

## Description

1,264 samples were sequenced at USUHS on the NovaSeq machine. FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 1,183 samples passed sequencing metrics and quality control checks.

## Cohorts

- [Cardiff EOAD](https://dss.niagads.org/cohorts/cardiff-eoad-2/)
- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)
- [National Centralized Repository for Alzheimer’s Disease and Related Dementias Family (NCRAD Family)](https://dss.niagads.org/cohorts/national-centralized-repository-for-alzheimers-disease-and-related-dementias-family-ncrad-family/)
- [NIA Alzheimer's Disease Research Centers (ADRC)](https://dss.niagads.org/cohorts/nia-alzheimers-disease-research-centers-adrc/)
- [Research in African-American Alzheimer’s Disease Initiative (REAAADI)](https://dss.niagads.org/cohorts/research-in-african-american-alzheimers-disease-initiative-reaaadi/)
- [Resource for Early-onset Alzheimer’s Disease Research (READR)](https://dss.niagads.org/cohorts/resource-for-early-onset-alzheimers-disease-research-readr/)
- [University of Miami (MIA)](https://dss.niagads.org/cohorts/university-of-miami-mia/)

## Sex

### Total number of samples: 1,183

Female62853.1 %

Male55546.9 %

## Race

### Total number of samples: 1,183

| Asian | 9 |
| --- | --- |
| Black or African American | 30 |
| White | 1,076 |
| Other | 62 |
| NA | 6 |

## Ethnicity

### Total number of samples: 1,183

Not Hispanic or Latino

1,085

91.7%

Hispanic or Latino

84

7.1%

Not Applicable/Not Available

14

1.2%

## Diagnosis

### Total number of samples: 1,183

| AD |  |  |
| --- | --- | --- |
| Control | 252 | 21.3% |
| Case | 651 | 55.0% |
| Other | 4 | 0.3% |
| Unknown | 276 | 23.3% |

## APOE

### Total number of samples: 1,183

- 226 (0.5%)
- 2382 (6.9%)
- 2419 (1.6%)
- 33529 (44.7%)
- 34376 (31.8%)
- 44160 (13.5%)
- NA11 (0.9%)