---
title: "FASe-Families2 WGS"
id: "7363"
type: "sample_set"
slug: "snd10101"
published_at: "2024-11-27T16:00:56+00:00"
modified_at: "2024-11-27T16:00:57+00:00"
url: "https://dss.niagads.org/sample-sets/snd10101/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10101.md"
excerpt: "659 samples were sequenced by USUHS and Macrogen on the NovaSeq and Illumina HiSeq 2500 platform. GCAD received FASTQ and CRAM files for processing. A total of 646 samples passed sequencing metrics and quality control checks."
---

## Description

659 samples were sequenced by USUHS and Macrogen on the NovaSeq and Illumina HiSeq 2500 platform. GCAD received FASTQ and CRAM files for processing. A total of 646 samples passed sequencing metrics and quality control checks.

## Cohorts

- [Knight Alzheimer’s Disease Research Center (KGAD)](https://dss.niagads.org/cohorts/knight-alzheimers-disease-research-center-kgad/)
- [National Centralized Repository for Alzheimer’s Disease and Related Dementias Family (NCRAD Family)](https://dss.niagads.org/cohorts/national-centralized-repository-for-alzheimers-disease-and-related-dementias-family-ncrad-family/)
- [National Institute of Aging Alzheimer’s Disease Family Based Study (NIA AD-FBS)](https://dss.niagads.org/cohorts/national-institute-on-aging-late-onset-of-alzheimers-disease-family-nia-load/)

## Sex

### Total number of samples: 646

Female41263.8 %

Male23436.2 %

## Race

### Total number of samples: 646

| Black or African American | 17 |
| --- | --- |
| White | 628 |
| Other | 1 |

## Ethnicity

### Total number of samples: 646

Not Hispanic or Latino

594

92.0%

Hispanic or Latino

1

0.2%

Not Applicable/Not Available

51

7.9%

## Diagnosis

### Total number of samples: 646

| AD |  |  |
| --- | --- | --- |
| Control | 51 | 7.9% |
| Case | 523 | 81.0% |
| Other | 33 | 5.1% |
| Unknown | 39 | 6.0% |

## APOE

### Total number of samples: 646

- 2331 (4.8%)
- 2420 (3.1%)
- 33204 (31.6%)
- 34270 (41.8%)
- 44109 (16.9%)
- NA12 (1.9%)