---
title: "NIA-AD-FBS1 WGS"
id: "7379"
type: "sample_set"
slug: "snd10105"
published_at: "2024-11-27T15:57:38+00:00"
modified_at: "2024-11-27T15:57:39+00:00"
url: "https://dss.niagads.org/sample-sets/snd10105/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10105.md"
excerpt: "A total of 999 NIA-FBS cohort samples were sequenced at NYGC on the Illumina HiSeqX platform. The BAM files were sent to GCAD for processing through the VCPA1.1 pipeline. A total of 997 samples passed sequencing metrics and quality control..."
---

## Description

A total of 999 NIA-FBS cohort samples were sequenced at NYGC on the Illumina HiSeqX platform. The BAM files were sent to GCAD for processing through the VCPA1.1 pipeline. A total of 997 samples passed sequencing metrics and quality control checks.

## Cohorts

- [National Institute of Aging Alzheimer’s Disease Family Based Study (NIA AD-FBS)](https://dss.niagads.org/cohorts/national-institute-on-aging-late-onset-of-alzheimers-disease-family-nia-load/)
- [University of Washington Families (RAS)](https://dss.niagads.org/cohorts/university-of-washington-families-ras/)

## Sex

### Total number of samples: 997

Female61661.8 %

Male38138.2 %

## Race

### Total number of samples: 997

| American Indian/Alaska Native | 8 |
| --- | --- |
| Asian | 16 |
| Black or African American | 93 |
| White | 872 |
| Other | 3 |
| NA | 5 |

## Ethnicity

### Total number of samples: 997

Not Hispanic or Latino

974

97.7%

Hispanic or Latino

18

1.8%

Not Applicable/Not Available

5

0.5%

## Diagnosis

### Total number of samples: 997

| AD |  |  |
| --- | --- | --- |
| Control | 348 | 34.9% |
| Case | 538 | 54.0% |
| Other | 82 | 8.2% |
| Unknown | 29 | 2.9% |

## APOE

### Total number of samples: 997

- 2337 (3.7%)
- 2420 (2.0%)
- 33291 (29.2%)
- 34412 (41.3%)
- 44190 (19.1%)
- NA47 (4.7%)