---
title: "SEA-AD Array data"
id: "7393"
type: "sample_set"
slug: "snd10109"
published_at: "2024-11-26T14:33:57+00:00"
modified_at: "2024-12-03T18:02:55+00:00"
url: "https://dss.niagads.org/sample-sets/snd10109/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10109.md"
excerpt: "80 samples from the SEA-AD cohort were genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium Global Screening Array (GSA-24v3-0_A1) BeadChip which captures genotype data on 654,027 genomic SNPs. The data was..."
---

## Description

80 samples from the SEA-AD cohort were genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium Global Screening Array (GSA-24v3-0_A1) BeadChip which captures genotype data on 654,027 genomic SNPs. The data was sent to the Alzheimer’s Disease Genetics Consortium (ADGC) at the University of Pennsylvania for processing. Genotypes were extracted from GenomeStudio2.0 into PLINK format. The genome build was lifted from GRCh37 to GRCh38, but no quality control procedures were implemented on the PLINK files.

## Cohorts

- [Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD)](https://dss.niagads.org/cohorts/sea-ad/)

## Sex

### Total number of samples: 80

Female4860.0 %

Male3240.0 %

## Race

### Total number of samples: 80

| Asian | 3 |
| --- | --- |
| White | 74 |
| Other | 3 |

## Ethnicity

### Total number of samples: 80

Not Hispanic or Latino

78

97.5%

Hispanic or Latino

1

1.3%

Not Applicable/Not Available

1

1.3%

## Diagnosis

### Total number of samples: 80

| AD |  |  |
| --- | --- | --- |
| Control | 8 | 10.0% |
| Case | 72 | 90.0% |

## APOE

### Total number of samples: 80

- 221 (1.3%)
- 2310 (12.5%)
- 242 (2.5%)
- 3346 (57.5%)
- 3416 (20.0%)
- 445 (6.3%)