---
title: "ROSMAP1 GWAS"
id: "9142"
type: "sample_set"
slug: "snd10134"
published_at: "2026-07-08T19:37:56+00:00"
modified_at: "2026-07-08T19:37:56+00:00"
url: "https://dss.niagads.org/sample-sets/snd10134/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10134.md"
excerpt: "The ROSMAP1 sample set was genotyped using the Affymetrix 6.0 BeadChip which captures genotype data on 906,600 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset. The..."
---

## Description

The ROSMAP1 sample set was genotyped using the Affymetrix 6.0 BeadChip which captures genotype data on 906,600 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline ([Naj et al. 2011](https://pubmed.ncbi.nlm.nih.gov/21460841/)
) was applied to this GWAS dataset. The final QC’d dataset is on GRCh38.

## Cohorts

- [Religious Orders Study/Memory and Aging Project (ROSMAP)](https://dss.niagads.org/cohorts/religious-orders-study-memory-and-aging-project-rosmap/)

## Sex

### Total number of samples: 1,668

Female75845.4 %

Male29917.9 %

Sex not reported: 611

## Race

### Total number of samples: 1,668

| White | 1,057 |
| --- | --- |
| NA | 611 |

## Ethnicity

### Total number of samples: 1,668

Not Hispanic or Latino

1,057

63.4%

Not Applicable/Not Available

611

36.6%

## Diagnosis

### Total number of samples: 1,668

| AD |  |  |
| --- | --- | --- |
| Control | 763 | 45.7% |
| Case | 294 | 17.6% |
| Unknown | 611 | 36.6% |

## APOE

### Total number of samples: 1,668

- 225 (0.3%)
- 23132 (7.9%)
- 2412 (0.7%)
- 33584 (35.0%)
- 34202 (12.1%)
- 4415 (0.9%)
- NA718 (43.0%)