---
title: "PITT GWAS"
id: "9465"
type: "sample_set"
slug: "snd10143"
published_at: "2026-10-06T18:58:13+00:00"
modified_at: "2026-10-27T18:56:11+00:00"
url: "https://dss.niagads.org/sample-sets/snd10143/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10143.md"
excerpt: "The PITT GWAS sample set was genotyped using the Illumina HumanOmni1-Quad BeadChip which captures genotype data on 1,016,423 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset...."
---

## Description

The PITT GWAS sample set was genotyped using the Illumina HumanOmni1-Quad BeadChip which captures genotype data on 1,016,423 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline ([Naj et al. 2011](https://pubmed.ncbi.nlm.nih.gov/21460841/)
) was applied to this GWAS dataset. The final QC’d dataset is on GRCh38.

## Cohorts

- [University of Pittsburgh (PITT)](https://dss.niagads.org/cohorts/university-of-pittsburgh-pitt/)

## Sex

### Total number of samples: 2,219

Female1,31559.3 %

Male76934.7 %

Sex not reported: 135

## Race

### Total number of samples: 2,219

| White | 2,084 |
| --- | --- |
| NA | 135 |

## Ethnicity

### Total number of samples: 2,219

Not Hispanic or Latino

2,084

93.9%

Not Applicable/Not Available

135

6.1%

## Diagnosis

### Total number of samples: 2,219

| AD |  |  |
| --- | --- | --- |
| Control | 829 | 37.4% |
| Case | 1,255 | 56.6% |
| Unknown | 135 | 6.1% |

## APOE

### Total number of samples: 2,219

- 228 (0.4%)
- 23155 (7.0%)
- 2454 (2.4%)
- 331,026 (46.2%)
- 34705 (31.8%)
- 44133 (6.0%)
- NA138 (6.2%)