---
title: "ACT and Genetic Differences GWAS"
id: "9577"
type: "sample_set"
slug: "snd10153"
published_at: "2026-10-27T18:55:25+00:00"
modified_at: "2026-10-27T18:56:12+00:00"
url: "https://dss.niagads.org/sample-sets/snd10153/"
markdown_url: "https://dss.niagads.org/sample-sets/snd10153.md"
excerpt: "The ACT sample set was genotyped using the Illumina Infinium HD Human660W-Quad BeadChip which captures genotype data on 657,366 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS..."
---

## Description

The ACT sample set was genotyped using the Illumina Infinium HD Human660W-Quad BeadChip which captures genotype data on 657,366 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline ([Naj et al. 2011](https://pubmed.ncbi.nlm.nih.gov/21460841/)
) was applied to this GWAS dataset. The final QC’d dataset is on GRCh38.

## Cohorts

- [Adult Changes in Thought (ACT)](https://dss.niagads.org/cohorts/adult-changes-in-thought-act/)