Overview
To access the full dataset, please log into DSS and submit an application.
Within the application, add this dataset (accession NG00110) in the “Choose a Dataset” section.
Once approved, you will be able to log in and access the data within the DARM portal.
The p-value only files are available in the “Open Access Dataset” tab.
Description
Summary statistics of the age-of-onset association analyses of AD using the WES ADSP discovery sample. Variants with missing rate >2% or MAC ≤10 in each of the analyses were not included in the tables. Model 1: a model with all subjects adjusted for three significant PCs and sex; Model 2: a model with all subjects adjusted for the copy of APOE ε4, three significant PCs and sex; Model 3: a model with APOE ε4 non-carriers adjusted for three significant PCs and sex. The positions of the SNPs are based on hg19.
In this study, we carried out an exome-wide association analysis of age-of-onset of Alzheimer’s disease with the cohort from the WES ADSP discovery phase and placed more emphasis on APOE ε4 non-carriers.
Available Filesets
| Name | Accession | Latest Release | Description |
|---|---|---|---|
| NG00110 Summary Statistics: p-value only (open access) | fsa000189 | NG00110.v1 | Summary Statistics (p-value only) |
| NG00110 Summary Statistics: full (application needed) | fsa000191 | NG00110.v2 | Summary Statistics (full) |
View the File Manifest for a full list of files released in this dataset.