• Data Type: 
    Single Cell RNA Sequencing
    Disease: 
    AD
    Platform: 
    10Xchemistry_v3
    Last Release Date: November 23, 2021
    Samples: 44
    Files: 14
    Total size: 1TB
    Alzheimer’s disease (AD) is the most prevalent cause of dementia. While there is no effective treatment for AD, a growing body of evidence points to passive immunotherapy with monoclonal antibodies against amyloid beta (Aβ) as a promising therapeutic strategy. Meningeal lymphatic drainage...
  • Data Type: 
    WESWGS
    Last Release Date: October 27, 2021
    Samples: 44,222
    Files: 85,524
    Total size: 584TB
    This dataset includes sequencing data from samples sequenced by the Alzhiemer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common workflow called VCPA (Variant Calling Pipeline and data management tool), a functionally equivalent CCDG/TOPMed pipeline....
  • Data Type: 
    GWAS
    Imputation: 
    1000GTOPMed
    Platform: 
    GSA
    Last Release Date: September 16, 2021
    Samples: 993
    Files: 57
    Total size: 64MB
    In 2018, 960 respondents from LASI-DAD who consented to the blood sample collection have been genotyped using Illumina Infinium genotyping platforms. The datasets being submitted include the original genotype assayed by the genotyping platforms, imputed data to the 1000G reference panel, as...
  • Data Type: 
    GWASSingle Cell RNA Sequencing
    Platform: 
    GSAHi-Seq
    Last Release Date: July 1, 2021
    Samples: 108
    Files: 323
    Total size: 1TB
    Human post-mortem brain samples were obtained from the Netherlands Brain Bank (NBB) and the Neuropathology Brain Bank and Research CoRE at Mount Sinai Hospital. The permission to collect human brain material was obtained from the Ethical Committee of the VU University Medical...