240+ approved Data Access Requests
NIAGADS DSS Data Summary
The ADSP has released whole-genomes for 4,750 subjects which includes CRAMs, gVCFs, a quality-controlled project level VCF and phenotypes. These data are available for qualified researchers to access. More information can be found on the ADSP Umbrella dataset page.
193.57 TBtotal size
NIAGADS DSS is currently hosting 4,750 whole genomes from the ADSP Discovery + Extension and ADNIWGS-1 phases. A breakdown by affection status and Ethnicity is shown here.
The next data release, planned for January 2020, will include about 20,000 whole-exomes from nine studies all called using the GCAD VCPA pipeline. The first release of the dataset will include CRAMs, gVCFs, and phenotypes for each sample. The second release, will include the ADSP QC’ed project level VCF.
GCAD is currently processing an additional 13,000 whole-genomes to be joint-called with the first whole-genome dataset, totaling about 18,000 whole-genomes. Joint calling of this dataset will begin in January 2020.
NIAGADS Data Summary
Data Availability and Types
All data derived from NIA funded Alzheimer’s Disease (AD) genetic studies are expected to be deposited in NIAGADS or another NIA approved site. As the NIA designated repository, NIAGADS has assisted with the deposition of genomic data of various types. Go to NIAGADS to view available datasets.