The Cardiff EOAD cohort was collected throughout England, Wales and Scotland and ascertained using a standard clinical assessment, together with detailed family ascertainment. Our ascertainment protocol used the UK Medical Research Council -AD clinical collection scales (validated for AD by Holmes et al. PMID: 10211150), an assessment based on the Manchester…
Cohort Country: United Kingdom
Stanford Extreme Phenotypes in AD (StEP AD)
This cohort contains samples from Brains for Dementia Research (BDR) Genetics project (Dr. Kevin Morgan, PI and Directory of the Alzheimer’s Research UK (ARUK) DNA Consortium and BDR). The BDR cohort and program was for planned brain donation across five UK brain banks and one donation point, with standardized operating…
Corticobasal Degeneration (CBD)
Patients with a clinical Parkinsonism in life and neuropathological confirmation of Corticobasal Degeneration (CBD) were identified from brain banks, research hospitals and neuropathologists. The top three contributing sites were the Mayo Clinic, University College London, and the University of Pennsylvania and additional small numbers of cases were obtained from various…
Progressive Supranuclear Palsy (PSP)
Patients with a clinical Parkinsonism in life and neuropathological confirmation of Progressive Supranuclear Palsy (PSP) were identified from brain banks, research hospitals and neuropathologists. The top three contributing sites were the Mayo Clinic, Harvard Brain Tissue Resource Center at McClean Hospital, and the University of Pennsylvania and additional small numbers…