To access the full dataset, please log into DSS and submit an application.
Within the application, add this dataset (accession NG00055) in the “Choose a Dataset” section.
Once approved, you will be able to log in and access the data within the DARM portal.

The p-value only files are available in the “Open Access Dataset” tab.

Description

Cerebrospinal fluid (CSF) tau, tau phosphorylated at threonine 181 (ptau), and Aβ₄₂ are established biomarkers for Alzheimer’s disease (AD) and have been used as quantitative traits for genetic analyses.  This is the largest genome-wide association study for cerebrospinal fluid (CSF) tau/ptau levels published to date (n >3000), and identified three genome-wide hits for CSF Aβ₄₂ and five loci for ptau levels.

Available Filesets

NameAccessionLatest ReleaseDescription
CSF Aβ/ptau: Full Summary Statistics (application needed)fsa000185NG00055.v1Full Summary Statistics
CSF Aβ/ptau: P-value only Summary Statistics (open access)fsa000186NG00055.v1P-values Only

View the File Manifest for a full list of files released in this dataset.