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Within the application, add this dataset (accession NG00087) in the “Choose a Dataset” section.
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Description

WashU2 GWAS is an SNP array dataset which contains AD cases and controls collected by the Knight Alzheimer’s Disease Research Center (ADRC) at Washington University. It consists of 38 cases, 94 healthy controls, and 103 other subjects that were used in analyses for this study. Participants were recruited as part of a longitudinal study of healthy aging and dementia. Diagnosis of dementia etiology was made in accordance with standard criteria and methods. Severity of dementia was assessed using the Clinical Dementia Rating scale. The dataset was analyzed within the stage 1 discovery dataset in the IGAP Kunkle et al. (2019) publication. Provided here are the PLINK genotype files that have undergone ADGC quality control procedures, covariates formatted by ADGC to be used with the genotype data, and imputation files (.bgen format) generated using the TOPMED-r2 reference panel.

Sample Summary per Data Type

Sample SetAccessionData TypeNumber of Samples
WashU2 GWASsnd10130Genotyping SNP Array235

Available Filesets

NameAccessionLatest ReleaseDescription
WashU2 GWAS: Genotype, covariate, and imputation filesfsa000156NG00087.v1Genotype, covariate, and imputation files

View the File Manifest for a full list of files released in this dataset.