Description

This project provides exome, genome, and genotyping SNP array data (both pre-imputation and post-imputation) for the University of Alabama at Birmingham (UAB) Alzheimer’s Disease Research Center. Participants are enrolled as either cognitively unimpaired, MCI, or a target of mild dementia and followed longitudinally. The cohort aims to recruit a substantial fraction of self-reported African American / Black participants.

Principal Investigators

  • J.Nicholas (Nick) Cochran — HudsonAlpha Institute for Biotechnology
  • Erik Roberson, MD, PhD — The University of Alabama Birmingham

Funding Sources

5P20AG068024

Publications

  • Wright CA. Contributions of rare and common variation to early-onset and atypical dementia risk. Cold Spring Harbor molecular case studies. 2023 Jun. PubMed link