Description
KnightADRC samples were sequenced at MGI on the HiSeq4000 machine. 75 samples were sequenced using the IDT xGen Exome Whole Exome Research Panel v1.0 w/Custom Spike-In Baits and 586 samples were using the Nimblegen VCRome sequencing w/Custom Spike-In Baits target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 650 passed sequencing metrics and quality control.
Sex
Total number of samples: 651
Female 335 51.5 %
Male 316 48.5 %
Race
Total number of samples: 651
| American Indian/Alaska Native | 2 |
| Asian | 2 |
| Black or African American | 31 |
| White | 615 |
| Other | 1 |
Ethnicity
Total number of samples: 651
Not Hispanic or Latino
33
5.1%
Hispanic or Latino
4
0.6%
Not Applicable/Not Available
614
94.3%
Diagnosis
Total number of samples: 653
| AD | ||
|---|---|---|
| Control | 347 | 53.1% |
| Case | 255 | 39.1% |
| Unknown | 51 | 7.8% |
APOE
Total number of samples: 651
- 223 (0.5%)
- 2360 (9.2%)
- 2424 (3.7%)
- 33310 (47.6%)
- 34197 (30.3%)
- 4441 (6.3%)
- NA16 (2.5%)