The AABC (formerly HCP-A) is working to uncover how brain structure and function changes as a normal part of aging by collecting and analyzing multimodal neuroimaging, behavioral, and genetic data. The specific goal of this analyses is to identify genetic variants associated with healthy aging.

Genotyping for these participants were generated through Illumina GSA v3.0 genotyping array and imputed using the TOPMed Reference Panel. Samples were QC’d using PLINK and retained using standard pipelines, resulting in 1,024 samples and 164,824,889 total variants (10,147,726 passing a 1% MAF threshold with a 98% call rate).

No phenotypes are provided with this dataset. Request phenotype data, APOE, and Polygenic Risk Scores via BALSA: https://balsa.wustl.edu/project?project=AABC