Description
FASe Family samples were sequenced at Genentech, MGI and Otogenetics on the HiSeq2000 machine. 715 samples were sequenced using the Agilent WES v5 capture region, 164 samples were using the Nimblegen VCRome sequencing w/Custom Spike-In Baits and 225 samples were using the Roche Nimblegen’s VCRome v2.1 target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 1041 passed sequencing metrics and quality control.
Sex
Total number of samples: 1,100
Female 670 60.9 %
Male 430 39.1 %
Race
Total number of samples: 1,100
| American Indian/Alaska Native | 4 |
| White | 1,096 |
Ethnicity
Total number of samples: 1,100
Not Hispanic or Latino
1,090
99.1%
Hispanic or Latino
10
0.9%
Diagnosis
Total number of samples: 1,148
| AD | ||
|---|---|---|
| Control | 278 | 24.2% |
| Case | 740 | 64.5% |
| Other | 84 | 7.3% |
| Unknown | 46 | 4.0% |
APOE
Total number of samples: 1,100
- 222 (0.2%)
- 2328 (2.5%)
- 2422 (2.0%)
- 33333 (30.3%)
- 34555 (50.5%)
- 44160 (14.5%)