FASe Family samples were sequenced at Genentech, MGI and Otogenetics on the HiSeq2000 machine. 715 samples were sequenced using the Agilent WES v5 capture region, 164 samples were using the Nimblegen VCRome sequencing w/Custom Spike-In Baits and 225 samples were using the Roche Nimblegen’s VCRome v2.1 target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 1041 passed sequencing metrics and quality control.

Total number of samples: 1,100

Female 670 60.9 %
Male 430 39.1 %

Total number of samples: 1,100

American Indian/Alaska Native4
White1,096

Total number of samples: 1,100

Not Hispanic or Latino
1,090
99.1%
Hispanic or Latino
10
0.9%

Total number of samples: 1,100

Disease
AD1,100100.0%
Study Specific Diagnosis
Control27825.3%
Case69262.9%
Other847.6%
Unknown464.2%

Total number of samples: 1,100

  • 222 (0.2%)
  • 2328 (2.5%)
  • 2422 (2.0%)
  • 33333 (30.3%)
  • 34555 (50.5%)
  • 44160 (14.5%)