KnightADRC samples were sequenced at MGI on the HiSeq4000 machine. 75 samples were sequenced using the IDT xGen Exome Whole Exome Research Panel v1.0 w/Custom Spike-In Baits and 586 samples were using the Nimblegen VCRome sequencing w/Custom Spike-In Baits target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 650 passed sequencing metrics and quality control.

Total number of samples: 650

Female 335 51.5 %
Male 315 48.5 %

Total number of samples: 650

American Indian/Alaska Native2
Asian2
Black or African American31
White614
Other1

Total number of samples: 650

Hispanic or Latino
4
0.6%
Not Applicable/Not Available
646
99.4%

Total number of samples: 650

Disease
AD650100.0%
Study Specific Diagnosis
Control34653.2%
Case25338.9%
Unknown517.8%

Total number of samples: 650

  • 223 (0.5%)
  • 2360 (9.2%)
  • 2424 (3.7%)
  • 33310 (47.7%)
  • 34195 (30.0%)
  • 4441 (6.3%)
  • NA17 (2.6%)