AMP-AD samples from the ROSMAP, MayoRNAseq, and Mount Sinai Brain Bank cohorts were whole-genome sequenced at New York Genome Center on the HiSeqX machine. FASTQ files were sent to GCAD for processing on the VCPA1.1 pipeline. 1326 samples passed sequencing metrics and quality control. Additional information about each of the three studies can be obtained from the AMP-AD Knowledge Portal.

Total number of samples: 1,326

Female 859 64.8 %
Male 467 35.2 %

Total number of samples: 1,326

Asian1
Black or African American33
White1,260
Other23
NA9

Total number of samples: 1,326

Not Hispanic or Latino
1,218
91.9%
Hispanic or Latino
24
1.8%
Not Applicable/Not Available
84
6.3%

Total number of samples: 1,326

Disease
AD1,24393.7%
PSP836.3%
Study Specific Diagnosis
Control46835.3%
Case81961.8%
Unknown392.9%

Total number of samples: 1,326

  • 228 (0.6%)
  • 23135 (10.2%)
  • 2422 (1.7%)
  • 33682 (51.4%)
  • 34321 (24.2%)
  • 4438 (2.9%)
  • NA120 (9.0%)