Description
AMP-AD samples from the ROSMAP, MayoRNAseq, and Mount Sinai Brain Bank cohorts were whole-genome sequenced at New York Genome Center on the HiSeqX machine. FASTQ files were sent to GCAD for processing on the VCPA1.1 pipeline. 1326 samples passed sequencing metrics and quality control. Additional information about each of the three studies can be obtained from the AMP-AD Knowledge Portal.
Sex
Total number of samples: 1,326
Female 859 64.8 %
Male 467 35.2 %
Race
Total number of samples: 1,326
| Asian | 1 |
| Black or African American | 33 |
| White | 1,260 |
| Other | 23 |
| NA | 9 |
Ethnicity
Total number of samples: 1,326
Not Hispanic or Latino
1,218
91.9%
Hispanic or Latino
24
1.8%
Not Applicable/Not Available
84
6.3%
Diagnosis Type
Total number of samples: 1,326
| Disease | ||
|---|---|---|
| AD | 1,243 | 93.7% |
| PSP | 83 | 6.3% |
| Study Specific Diagnosis | ||
|---|---|---|
| Control | 468 | 35.3% |
| Case | 819 | 61.8% |
| Unknown | 39 | 2.9% |
APOE
Total number of samples: 1,326
- 228 (0.6%)
- 23135 (10.2%)
- 2422 (1.7%)
- 33683 (51.5%)
- 34321 (24.2%)
- 4438 (2.9%)
- NA119 (9.0%)