The AMP-AD WGS sampleset was sequenced on the Illumina HiSeqX sequencer (v2.5 chemistry) and made available from four aging and Alzheimer’s disease cohorts: Religious Orders Study (ROS) and Memory and Aging Project (MAP), Mayo Clinic, and Mount Sinai Brain Bank (MSBB). Structural variation discovery quality control identified 46,197 SVs in Mayo Clinic (349 samples), 52,451 SVs in MSBB (305 samples), and 72,348 SVs in ROS/MAP (715 samples), totaling 170,966 across 1,369 samples. Subjects in ROS/MAP not consented for individual SV calls were removed from the individual level data submission but are still part of the aggregate association summary statistics.

Total number of samples: 1,369

Female 866 63.3 %
Male 503 36.7 %

Total number of samples: 1,369

NA1,369

Total number of samples: 1,369

Not Applicable/Not Available
1,369
100.0%

Total number of samples: 1,369

AD
Control29421.5%
Case54039.4%
PSP
Case836.1%
Other
Other45233.0%

Total number of samples: 1,369

  • 227 (0.5%)
  • 23133 (9.7%)
  • 2414 (1.0%)
  • 33695 (50.8%)
  • 34285 (20.8%)
  • 4427 (2.0%)
  • NA208 (15.2%)