Description
Sample selection and genotyping was coordinated and paid for by the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD). NCRAD supported genotyping of samples from subjects with diagnoses other than AD, MCI, or cognitively normal. The ADC15 sample set was genotyped by the Center for Applied Genomics at the Children’s Hospital of Philadelphia using the Illumina Infinium Global Screening Array (GSA-24v3-0_A1) BeadChip which captures genotype data on 654,027 genomic SNPs. The standard Alzheimer’s Disease Genetics Consortium (ADGC) quality control pipeline (Naj et al. 2011) was applied to this GWAS dataset.
Sex
Total number of samples: 894
Female 551 61.6 %
Male 343 38.4 %
Race
Total number of samples: 894
| American Indian/Alaska Native | 1 |
| Asian | 37 |
| Native Hawaiian or Other Pacific Islander | 1 |
| Black or African American | 107 |
| White | 731 |
| Other | 7 |
| NA | 10 |
Ethnicity
Total number of samples: 894
Not Hispanic or Latino
826
92.4%
Hispanic or Latino
55
6.2%
Not Applicable/Not Available
13
1.5%
Diagnosis
Total number of samples: 894
| AD | ||
|---|---|---|
| Control | 620 | 69.4% |
| Case | 17 | 1.9% |
| Unknown | 257 | 28.7% |
APOE
Total number of samples: 894
- 228 (0.9%)
- 2376 (8.5%)
- 2421 (2.3%)
- 33459 (51.3%)
- 34272 (30.4%)
- 4458 (6.5%)