The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) aims are to: conduct a genetically sensitive study of individual differences in behavioral and cognitive change at the cusp of middle adulthood, in participants from the Colorado Adoption Project (CAP) and Longitudinal Twin Study (LTS) studied almost yearly from birth to early adulthood; map individual differences in growth and maintenance of cognitive abilities; evaluate and trace measured physical factors and health behaviors, biochemical markers and measured genetic pathways important to sustaining cognitive performance; and track measured environmental factors that might decrease, sustain or boost cognitive performance. (R01 AG046938 co-PI’s: Reynolds (contact), Wadsworth)

Chandra A. Reynolds, Ph.D.
University of Colorado Boulder

Sally J. Wadsworth, Ph.D.
University of Colorado Boulder

Acknowledgment statement for any data distributed by NIAGADS:

Data for this study were prepared, archived, and distributed by the National Institute on Aging Alzheimer's Disease Data Storage Site (NIAGADS) at the University of Pennsylvania (U24-AG041689), funded by the National Institute on Aging.

For investigators using The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) data:

The Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife) project is supported by the National Institute on Aging (grant number NIA R01AG046938) and conducted at the University of Colorado Boulder.

  • Reynolds, C. A., Smolen, A., Corley, R. P., Munoz, E., Friedman, N. P., Rhee, S. H., Stallings, M. C., DeFries, J. C., & Wadsworth, S. J. (2019, Dec). APOE effects on cognition from childhood to adolescence. Neurobiol Aging, 84, 239.e231-239.e238. https://doi.org/10.1016/j.neurobiolaging.2019.04.011 PubMed link
  • Wadsworth, S. J., Corley, R. P., Munoz, E., Trubenstein, B. P., Knaap, E., DeFries, J. C., Plomin, R., & Reynolds, C. A. (2019, Dec). CATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning. Twin Res Hum Genet, 22(6), 695-706. https://doi.org/10.1017/thg.2019.49 PubMed link