The fourth release from the Alzheimer’s Disease Sequencing Project Phenotype Harmonization Consortium (ADSP-PHC), which includes harmonized phenotypes for ADSP participants with sequencing, is available in the ADSP Umbrella Dataset (NG00067v20). Importantly, this release includes harmonized diagnosis and plasma biomarkers for the first time. Existing users with approval for NG00067 will have access…
Tag: ADSP
NIAGADS Data Discovery Portal Beta Release: Gen3 Enables Exploration of the ADSP Dataset
One of the first challenges researchers face when accessing data is determining if the dataset has information relevant to their research question. The NIAGADS team is committed to reducing this burden for researcher through NIAGADS Open Access, a suite of knowledge bases to help explore the NIAGADS data collection and…
Creating the Largest Joint-Called Whole Exome Sequencing (WES) Dataset for Alzheimer’s Disease (AD)
Over the last 20 years, the technology for DNA sequencing has rapidly evolved, making it possible to sequence individual whole genomes on a large scale. But when trying to find the underlying genetic causes of disease, every sequence donated matters. How can the sequences generated using older technology be reused?…