Description

The Amyloid Neuroimaging and Genetics Initiative (ANGI) is an add-on study for people who had participated in the IDEAS (Imaging Dementia—Evidence For Amyloid Scanning) Study. The IDEAS-Study is nationwide research study for people who have memory loss to investigate amyloid PET scan. The goal of the ANGI study is to pair the clinical information and brain imaging data collected in the IDEAS-Study, or other related studies, with DNA obtained from a saliva sample. In addition to IDEAS study data, participants enrolled in ANGI provided demographic information. The ANGI DNA samples are banking at NCRAD and can be requested for additional research studies.

Principal Investigators

  • Tatiana Foroud, PhD — Indiana University School of Medicine
  • Andrew Saykin, PhD — Indiana University School of Medicine

Funding Sources

Alzheimer’s Association Grant: ANGI/IDEAS-17-497186 and U24AG021886

Publications

  • Rabinovici GD. Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia. JAMA. 2019 Apr 2. PubMed link