ADSP Phenotype Harmonization Consortium Release 3 is Out!

The third release from the Alzheimer’s Disease Sequencing Project Phenotype Harmonization Consortium (ADSP-PHC), which includes harmonized phenotypes ADSP participants with sequencing, is available in the ADSP Umbrella Dataset (NG00067v15). Existing users with approval for NG00067 will have access to PHC release 3 in alignment with their approved consent levels. The…

Join NIH “Community” Days to Learn About GDS Policy Updates Effective 1/25/25

The National Institutes of Health (NIH) will be holding “Community Days” on: Registration is required. Please use the links above to register for the day you plan to attend. ASL will be provided. Who Should Attend: All researchers and their institutional officials who have access to or are planning to…

The NIAGADS Pre-Print Paper is Live at medRXiv

The NIAGADS team has been hard at work putting together a publication covering all things NIAGADS, including the immense amount of work that take place behind the scenes. The article contains: We ask that data users cite this paper when publishing articles involving NIAGADS datasets as well as acknowledging NIAGADS…

ADSP R5 WGS Preview Files are Here!

Round 5 of the Alzheimer’s Disease Sequencing Project (NG00067v14) has been released! This release contains 22,158 new samples and 17 new cohorts, bringing the total number of genomes in the R5 release to 58,507 genomes from 57 cohorts. Files include the following: GCAD has implemented a new joint-genotype caller, GLnexus,…

The ADSP and NIAGADS Will be at ASHG 2024, From 11/5 Through 11/9, in Denver, Colorado

Are you going to be at the American Society for Human Genetics (ASHG) 2024 Annual Meeting being held in Denver, Colorado from this Tuesday, 11/05/24, to Saturday, 11/09/24? The ADSP and NIAGADS will be there too! Check out where you can see the ADSP and NIAGADS in action below: ADSP…

New Data Available in the Alzheimer’s GenomicsDB!

This release expands the database to include: ADSP 36K R4 Variants and Annotations  New and updated records for each R4 variant are now available.  These include the most recent ADSP annotations, as well as updated associations from the NHGRI-EBI GWAS Catalog.   Search for a specific variant of interest to browse…

ADSP Umbrella Dataset October 2024 Update: New Files Added to NG00067

New files have been released in ng00067.v13 for the R2 20K Whole Exome Sequencing (WES) and R3 17K and R4 36K Whole Genome Sequencing (WGS). To apply for this dataset, see our application guide. For those who already have access to NG00067, files will be automatically available in compliance with…

NIAGADS Data Discovery Portal Beta Release: Gen3 Enables Exploration of the ADSP Dataset 

One of the first challenges researchers face when accessing data is determining if the dataset has information relevant to their research question. The NIAGADS team is committed to reducing this burden for researcher through NIAGADS Open Access, a suite of knowledge bases to help explore the NIAGADS data collection and…

A Year of Support and Resource Improvements at NIAGADS

The last 12 months have been a year of growth for user support and resources at NIAGADS. The team was hard at work developing and improving documentation, tutorials, and more.  Ticket System  NIAGADS now has a dedicated ticket system for users to submit questions and technical issues. The ticket system…