Participants include persons of Mexican origin affected by or known to be at 50% risk for the development of autosomal dominant Alzheimer’s disease (ADAD) due to the A431E mutation in PSEN1 or the V717I mutation in APP. This includes legacy DNA and data collected prior to funding and prospective data…
Cohort Category: ADSP
Health and Aging Brain Study – Health Disparities (HABS-HD)
This study is a single site project that is conducted at the University of North Texas Health Science Center. The DFW metroplex currently represents the future racial/ethnic distribution of the U.S. and is a unique setting to simultaneously study factors associated with MCI/AD among African Americans, Hispanics and non-Hispanic Whites.…
Arizona APOE Cohort Study
Cognitively unimpaired 50-90-year-old persons with each common form of APOE genotype providing blood and cerebrospinal fluid samples obtained utilizing the NCRAD protocol with storage and management through NCRAD, amyloid and tau PET and MRI brain imaging data compliant with the SCAN Initiative, and cognitive and behavioral assessment data including the…
Healthy Elderly Active Longevity (HEAL) Cohort “Wellderly”
This study began enrollment at the end of 2007 and included eligible individuals 80 years of age or older, which was later changed to 85 years of age or older. The objective of this study is to obtain blood and/or saliva samples in order to help model health and disease…
Korean Brain Aging Study for the Early Diagnosis and Prediction of AD (KBASE)
Korean Brain Aging Study for the Early Diagnosis and Prediction of AD (KBASE) is a prospective cohort study launched at Seoul National University (SNU) in 2014 using a similar design and methods as the North American Alzheimer’s Disease Neuroimaging Initiative (ADNI). The KBASE cohort consists of well-characterized participants including cognitively normal…
Interaction between SARS-CoV-2 Infection and Ancestral genomic Variations in the Risk of Alzheimer’s Disease and Related Disorders (ISAVRAD)
ISAVRAD is a longitudinal study of older adult Amerindians from Northern Argentina with or without exposure to SARS-CoV-2 infection to understand the impact of interactions between ancestral genomic variants and infection on the risk of cognitive decline and ADRD. With funding from the Alzheimer’s Association and Fundacion FULTRA, 875 participants…