Description
Columbia WHICAP samples were sequenced at IGM- Columbia University on the HiSeq2000 machine. 1130 African American, 1829 Hispanic and 896 Caucasian samples were sequenced using the Roche SeqCap EZ Exome Probes v3.0 Target Enrichment Probes. BAM files from hg38 build were sent to GCAD for processing on the VCPA1.1 pipeline. 3170 passed sequencing metrics and quality control.
Sex
Total number of samples: 3,861
Female 2,636 68.3 %
Male 1,225 31.7 %
Race
Total number of samples: 3,861
| American Indian/Alaska Native | 1 |
| Black or African American | 1,171 |
| White | 886 |
| Other | 1,803 |
Ethnicity
Total number of samples: 3,861
Not Hispanic or Latino
2,057
53.3%
Hispanic or Latino
1,804
46.7%
Diagnosis
Total number of samples: 3,863
| AD | ||
|---|---|---|
| Control | 2,998 | 77.6% |
| Case | 812 | 21.0% |
| Unknown | 53 | 1.4% |
APOE
Total number of samples: 3,861
- 2225 (0.6%)
- 23501 (13.0%)
- 24104 (2.7%)
- 332,295 (59.4%)
- 34865 (22.4%)
- 4466 (1.7%)
- NA5 (0.1%)