Columbia WHICAP samples were sequenced at IGM- Columbia University on the HiSeq2000 machine.  1130 African American, 1829 Hispanic and 896 Caucasian samples were sequenced using the Roche SeqCap EZ Exome Probes v3.0 Target Enrichment Probes. BAM files from hg38 build were sent to GCAD for processing on the VCPA1.1 pipeline. 3170 passed sequencing metrics and quality control.

Total number of samples: 3,861

Female 2,634 68.2 %
Male 1,227 31.8 %

Total number of samples: 3,861

American Indian/Alaska Native1
Black or African American1,171
White886
Other1,803

Total number of samples: 3,861

Not Hispanic or Latino
2,057
53.3%
Hispanic or Latino
1,804
46.7%

Total number of samples: 3,861

Disease
AD3,861100.0%
Study Specific Diagnosis
Control2,99877.6%
Case81021.0%
Unknown531.4%

Total number of samples: 3,861

  • 2225 (0.6%)
  • 23501 (13.0%)
  • 24104 (2.7%)
  • 332,295 (59.4%)
  • 34864 (22.4%)
  • 4467 (1.7%)
  • NA5 (0.1%)