The Center for Cognitive Neuroscience and Aging (CNSA) at the University of Miami is a center focused on the evaluation, management, treatment and care for older persons and their families with memory and other brain disorders affecting cognition. A major focus of this group is early detection of cognitive impairment.…
Cohort Category: ADSP
Gwangju Alzheimer’s and Related Dementia (GARD)
The Gwangju Alzheimer’s and Related Dementias (GARD) Cohort is a prospectively followed sample of persons in a senior citizen’s community located in the South Korean southwestern city of Gwangju. A large portion of the cohort has been evaluated with the Seoul Neuropsychological Screening Battery (SNSB) and had a brain MRI scan, and…
Portuguese Alzeimer’s Disease Cohort
Description coming soon.
ASPrin in Reducing Events in the Elderly (ASPREE) & ASPREE-XT
ASPREE is a randomized, double-blind, placebo-controlled clinical trial investigating the effects of 100mg of daily low-dose aspirin in 19,114 healthy older adults, aged ≥70 years (≥65 years for US participants) at enrollment. ASPREE-XT is an ongoing observational follow-up study to examine the long-term effects of aspirin on various health outcomes,…
A4 Study (A4)
The A4 Study was designed as a three-year, placebo-controlled, randomized clinical trial to test whether anti-amyloid treatment can slow the rate of cognitive decline in older individuals from diverse ethnic-racial backgrounds (non-Hispanic White, African American and Latino/Hispanic) with evidence of amyloid accumulation on screening PET scans.
Puerto Rican Alzheimer’s Disease Initiative (PRADI)
The Puerto Rican Alzheimer’s Disease Initiative (PRADI) is a NIH NIA study of late-onset Alzheimer disease focused on the Caribbean-Hispanic Puerto Rican population. Participants were ascertained for an AD/ADRD Memory Study, including healthy controls. Eligibility was based on self-reported Puerto Rican heritage. Most participants were recruited in the Island of Puerto Rico…
Peru Alzheimer’s Disease Initiative (PeADI)
The Peru Alzheimer’s Disease Initiative (PeADI) is being conducted at several sites in Peru including Lima (Marca-Ysabel et al. 2021). The Mestizo population living in Lima, the capital city, is comprised of ~76% of Amerindian, 11% Southern European, and 3% Northern African ancestries, and a smaller proportion of western central Africa, western…
Northern Manhattan Study (NOMAS)
The Northern Manhattan Study (NOMAS) is a research study of stroke and stroke risk factors among the multi-ethnic community of Northern Manhattan, New York. The study is a collaboration between the Department of Neurology at University of Miami and the Neurological Institute at Columbia University. NOMAS is a NINDS-funded study of the population…
Longevity Genes Project (LGP)
The Longevity Genes Project (LGP), established in 1998 at Albert Einstein College of Medicine, recruits Ashkenazi Jewish centenarians (age 95 and older) who are in general good health at age 95, offspring of centenarians, and spouses of offspring in the Eastern United States. The goal of this cross-sectional study is…
LonGenity
The LonGenity study at Albert Einstein College of Medicine has been recruiting community dwelling Ashkenazi Jewish seniors aged 65 or older in the United States since 2008. Offspring of Parents with Exceptional Longevity (OPEL), defined by having at least one parent who lived to age 95 or older and Offspring…