Participants were enrolled in the Hillblom Aging Network at the University of California, San Francisco (UCSF) Memory and Aging Center. All participants underwent comprehensive neurobehavioral evaluations and met the following inclusionary criteria at baseline: 1) clinically normal based on consensus conference with a neurologist and board-certified neuropsychologist; 2) no history…
Cohort Category: ADSP
Research in African-American Alzheimer’s Disease Initiative (REAAADI)
The Research in African-American Alzheimer’s Disease Initiative (REAAADI) is a NIH NIA study focused on identifying genetic factors for Alzheimer disease within the African-American population in order to detect new targets for drug development and improve accessibility to Alzheimer’s disease education within the community. Participants were ascertained for multiple studies of AD/ADRD…
University of Miami Brain Bank (MBB)
The University of Miami Brain Bank Cohort was ascertained through self-referred cases and controls to the University of Miami Brain Endowment Bank, a National Institutes of Health (NIH) NeuroBioBank, one of six designated brain and tissue biorepositories in the nation. Medical records are available on all cases and controls, all…
Mexican Health and Aging Study (MHAS)
The Mexican Health and Aging Study (MHAS) is a national longitudinal study of adults 50 years and older in Mexico. The baseline survey, with national and urban/rural representation of adults born in 1951 or earlier, was conducted in 2001 with follow-up interviews in 2003, 2012, 2015, and 2018. A new…
Case Western Reserve University (CWRU) Autopsy
The Case Western Reserve University (CWRU) Autopsy Cohort was an Alzheimer’s Disease Research Center (ADRC) clinic-based sample. Subjects included in the Case Western Reserve Autopsy cohort include individuals who were participants in the Brain Health and Memory Center Research Brain Donation Protocol at University Hospitals Cleveland Medical Center in Cleveland,…
Amish Protective Variant Study
The Amish Protective Variant Study, based at Case Western Reserve University and the University of Miami (Cummings et al. 2012; D’Aoust et al. 2015), is being conducted in the Indiana and Ohio Old Order Amish (OOA) population. The OOA, an isolated founder population originating from emigration of German and Swiss…
Cuban American Alzheimer’s Disease Initiative (CuAADI)
The Cuban American Alzheimer’s Disease Initiative (CuAADI) is a convenience sample ascertained through community outreach to Alzheimer’s and adult day care centers in Southern Florida, lay conferences, and Neurology and Memory Disorders clinics. Eligibility was based on self-reported Cuban heritage. The participants were recruited in South Florida which is home to the…
Case Western Reserve University (CWRU) Rapid Decline
The Case Western Reserve University (CWRU) Rapid Decline Cohort (Cohen et al. 2015) represents patients with rapid decline. Subjects included in the Case Western Reserve Rapid Decline dataset include individuals who were initially suspected of having Creutzfelt-Jakob disease (CJD). The Brains of these individuals were obtained by the National Prion…
Wisconsin Registry for Alzheimer’s Prevention (WRAP)
The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is an ongoing longitudinal observational cohort study of individuals age 40-65 at baseline who do not have dementia. Since 2001, WRAP has enrolled more than 1,700 individuals, 73% of whom had a parental history of probable Alzheimer’s disease (AD) dementia. Participants return for…
Health and Retirement Study (HRS)
The HRS is a nationally representative sample with oversamples of African-American and Hispanic populations. The target population for the original HRS cohort includes all adults in the contiguous United States born during the years 1931–1941 who reside in households. HRS was subsequently augmented with additional cohorts in 1993 and 1998…